Description

2-Chloro-5-Iodo-3-Methylthiophene is a high-purity halogenated thiophene derivative, a crucial building block in advanced organic synthesis. Its unique structure, featuring both chlorine and iodine substituents, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating complex heterocyclic cores.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the thiophene scaffold imparts specific biological activity.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and solar cells.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) due to the reactive iodine moiety, enabling further functionalization.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized dyes and pigments with unique optical properties.

Basic Information

Product Name	2-Chloro-5-Iodo-3-Methylthiophene
CAS No.	1450592-72-9
Molecular Formula	C5H4ClIS
Molecular Weight	258.50 g/mol
Synonyms	3-Methyl-2-chloro-5-iodothiophene; 5-Iodo-2-chloro-3-methylthiophene; 2-Chloro-3-methyl-5-iodothiophene; Thiophene, 2-chloro-5-iodo-3-methyl-; 2-Chloro-5-iodo-3-methylthiophene; 1450592-72-9; Halogenated Thiophene Derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Iodo-3-Methylthiophene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Typical: 98-99%)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.