Description

5-Bromo-2H-Pyrazolo[3,4-B]Pyridine is a high-value brominated heterocyclic building block, specifically a pyrazolopyridine derivative, with the CAS registry number 1449693-24-6. This compound is essential for medicinal chemistry research and development, serving as a key synthetic intermediate for creating novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of advanced drug candidates and agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Serves as a precursor in the creation of new herbicides and fungicides with novel modes of action.
• Material Science: Potential monomer or precursor for the development of specialty polymers and organic electronic materials.
• Chemical Biology: Used as a molecular probe or tag in biochemical assay development and target identification.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Item	Detail
Product Name	5-Bromo-2H-Pyrazolo[3,4-B]Pyridine
CAS No.	1449693-24-6
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	5-Bromo-2H-pyrazolo[3,4-b]pyridine; 5-Bromo-1H-pyrazolo[3,4-b]pyridine; 5-Bromopyrazolo[3,4-b]pyridine; 1449693-24-6; 5-Bromo-2H-pyrazolo[3,4-b]pyridine; 5-Bromo-1H-pyrazolo[3,4-b]pyridine; 5-Bromopyrazolo[3,4-b]pyridine; 5-Bromo-2H-pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.