Description

Bis(2,5-Dioxopyrrolidin-1-Yl) 4,4'-(1,2-Diphenylethane-1,2-Diyl)Dibenzoate is a specialized chemical intermediate featuring a bifunctional activated ester structure. This compound matters for its role as a high-performance cross-linking and conjugation agent, enabling the formation of stable amide bonds under mild conditions. It is primarily needed by researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors for developing novel drug delivery systems, polymer networks, and diagnostic reagents.

Application

• Bioconjugation Reagent: For coupling peptides, proteins, or antibodies to other biomolecules, surfaces, or polymeric carriers.
• Pharmaceutical Intermediate: In the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutic agents.
• Polymer Cross-Linker: Used in the production of hydrogels, resins, and other polymeric materials requiring controlled cross-linking density.
• Surface Functionalization: For modifying nanoparticles, chips, or solid supports to introduce reactive groups for further chemical attachment.
• Diagnostic Assay Development: In the preparation of enzyme-linked immunosorbent assay (ELISA) components and other diagnostic tools.
• Materials Science Research: As a building block for creating novel organic frameworks and functional materials with specific properties.

Basic Information

Item	Detail
Product Name	Bis(2,5-Dioxopyrrolidin-1-Yl) 4,4'-(1,2-Diphenylethane-1,2-Diyl)Dibenzoate
CAS No.	1449572-34-2
Molecular Formula	C36H28N2O8
Molecular Weight	616.62 g/mol
Synonyms	1,1'-(1,2-Diphenylethane-1,2-diyl)bis(4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate); 4,4'-(1,2-Diphenylethane-1,2-diyl)bis(oxycarbonyl)bis(1H-pyrrole-2,5-dione); Bis(N-hydroxysuccinimide) ester of 4,4'-(1,2-Diphenylethane-1,2-diyl)dibenzoic acid; Bis(NHS) ester of stilbene dicarboxylic acid derivative; Bifunctional NHS ester crosslinker; Activated ester cross-linking agent; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our Bis(2,5-Dioxopyrrolidin-1-Yl) 4,4'-(1,2-Diphenylethane-1,2-Diyl)Dibenzoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label/COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.