Description

6-Chloro-2-Fluoro-3-Iodobenzyl Alcohol is a high-purity, multi-halogenated benzyl alcohol derivative serving as a critical advanced pharmaceutical intermediate. Its unique halogen substitution pattern makes it a valuable synthon for constructing complex molecules in medicinal chemistry. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its halogenated aromatic structure.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and liquid crystals.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitutions to introduce complex benzyl motifs.
• Diagnostic Agent Development: Potential precursor for radiolabeling (using Iodine-123/125) in the creation of imaging probes for PET/SPECT.
• Academic & Contract Research: Essential for methodological studies and library synthesis in academic and CRO laboratory settings.

Basic Information

Product Name	6-Chloro-2-Fluoro-3-Iodobenzyl Alcohol
CAS No.	1449008-32-5
Molecular Formula	C7H5ClFIO
Molecular Weight	301.47 g/mol
Synonyms	(6-Chloro-2-fluoro-3-iodophenyl)methanol; 1-(Chloro)-2-(fluoro)-3-(iodo)-6-(hydroxymethyl)benzene; 2-Fluoro-6-chloro-3-iodobenzyl alcohol; 3-Iodo-6-chloro-2-fluorobenzyl alcohol; Benzenemethanol, 6-chloro-2-fluoro-3-iodo-; 1449008-32-5; CAS 1449008-32-5
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Fluoro-3-Iodobenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports cGMP and ISO standards for reliable integration into regulated synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.