Description

Ethyl 2-Cinnamamido-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for research and development in medicinal chemistry. This compound is valued for its role as a key synthetic building block in the creation of novel therapeutic agents, particularly those targeting complex biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and contract manufacturing organizations (CMOs) engaged in the synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those with a tetrahydrobenzo[b]thiophene core structure.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity for new therapeutic targets.
• API Development: Serves as a building block in the development and scale-up processes for potential Active Pharmaceutical Ingredients (APIs).
• Biochemical Tool Compound: May be utilized in biochemical assays and as a probe to study specific enzyme or receptor interactions in early-stage discovery.
• Custom Synthesis: Employed by fine chemical suppliers for the custom synthesis of specialized compounds for client-specific research programs.

Basic Information

Product Name	Ethyl 2-Cinnamamido-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate
CAS No.	1448530-61-7
Molecular Formula	C22H23NO3S
Molecular Weight	381.49 g/mol
Synonyms	Ethyl 2-[(E)-3-phenylprop-2-enamido]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 2-Cinnamamido-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic Acid Ethyl Ester; Benzo[b]thiophene-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(2E)-3-phenyl-2-propenoyl]amino]-, ethyl ester; Ethyl 2-cinnamamidotetrahydrobenzo[b]thiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Cinnamamido-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.