Description

Oxibendazole-Amine-D7 is a deuterated analog of the oxibendazole amine intermediate, specifically labeled with seven deuterium atoms. This compound is essential for the development and validation of highly sensitive and accurate analytical methods, particularly in mass spectrometry-based applications. It serves as a critical internal standard for researchers and quality control laboratories in the pharmaceutical and veterinary medicine sectors, enabling precise quantification and metabolic studies of the parent benzimidazole anthelmintic.

Application

• Primary use as an internal standard for the quantification of oxibendazole and related metabolites in biological matrices via LC-MS/MS.
• Facilitates drug metabolism and pharmacokinetic (DMPK) studies in veterinary and pharmaceutical research.
• Critical for residue testing and method development in food safety and regulatory compliance for animal-derived products.
• Supports bioanalytical method validation to meet FDA, EMA, and other international regulatory guidelines.
• Used in stable isotope labeling research to trace metabolic pathways.
• Essential reference material for quality control in the synthesis of deuterated active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Oxibendazole-Amine-D7
CAS No.	1448346-35-7
Molecular Formula	C12H8D7N3O2
Molecular Weight	~ 249.3 g/mol
Synonyms	5-Propoxy-2-(aminobenzimidazole)-D7; Methyl 5-propoxy-1H-benzimidazol-2-ylcarbamate-D7 amine; Oxibendazole amine deuterated; Oxibendazole-D7 amine intermediate; [2H7]-Oxibendazole amine; Benzimidazole-2-amine, 5-propoxy-, D7 labeled; Deuterated oxibendazole precursor; Internal Standard for Oxibendazole
EINECS	Contact for details

Quality Control

Our Oxibendazole-Amine-D7 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and isotopic enrichment (typically ≥98% chemical purity and ≥99% deuterium incorporation). Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability and compliance with your research or quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the material should be handled in a dry environment and consideration should be given to storage under an inert atmosphere for long-term preservation of stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D7)	≥ 99.0 atom % D
Chemical Purity (by NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.