Description

Neutrophil Elastase Inhibitor CAS NO 1448314-31-5 is a potent and selective small molecule compound designed to target and inhibit the activity of neutrophil elastase, a key enzyme involved in inflammatory processes. This inhibition is crucial for modulating tissue damage and inflammation in various pathological conditions. It is an essential research tool and a promising candidate for therapeutic development, primarily targeted at pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on inflammatory and respiratory diseases.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the development of novel therapeutics for neutrophil-driven inflammatory disorders.
• Biochemical & Mechanistic Studies: Used in in vitro and in vivo models to elucidate the role of neutrophil elastase in disease pathways such as chronic obstructive pulmonary disease (COPD), acute lung injury, and cystic fibrosis.
• Preclinical Candidate Screening: Employed in high-throughput screening assays to evaluate the efficacy and selectivity of new drug candidates targeting serine proteases.
• Academic & Institutional Research: A vital reagent for universities and research institutes studying inflammation, immunology, and protease biology.
• Biomarker & Diagnostic Development: Can be utilized in the development of assays to measure elastase activity or inhibition as a biomarker for disease progression or therapeutic response.

Basic Information

Product Name	Neutrophil Elastase Inhibitor
CAS No.	1448314-31-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NE Inhibitor; Human Neutrophil Elastase (HNE) Inhibitor; Elastase Inhibitor, Neutrophil; Serine Protease Inhibitor; 1448314-31-5; (Compound code specific to manufacturer); Leukocyte Elastase Inhibitor
EINECS	Contact for details

Quality Control

Our Neutrophil Elastase Inhibitor is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, MS) and purity assessment by high-performance liquid chromatography (HPLC). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This compound is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Biological Activity (IC50)	Reported per batch

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.