Description

1,2,3,4-Tetrahydroisoquinolin-8-Amine Hcl is a high-purity organic compound serving as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile amine-protected intermediate, enabling the development of complex molecular architectures. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where precise and reliable intermediates are paramount for innovation.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds and natural product analogs.
• Material Science: Investigated as a monomer or functional additive in the creation of specialty polymers and advanced materials.
• Chemical Biology: Utilized as a probe or linker in the study of biological pathways and enzyme interactions.
• Catalyst Ligand Synthesis: Serves as a starting material for the preparation of novel ligands used in asymmetric catalysis.

Basic Information

Product Name	1,2,3,4-Tetrahydroisoquinolin-8-Amine Hcl
CAS No.	1447606-38-3
Molecular Formula	C9H13ClN2
Molecular Weight	184.67 g/mol
Synonyms	8-Amino-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-8-isoquinolinamine hydrochloride; 8-Aminotetrahydroisoquinoline HCl; THIQ-8-Amine hydrochloride; 1,2,3,4-Tetrahydroisoquinolin-8-ylamine hydrochloride; 8-Amino-THIQ HCl; 1447606-38-3
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydroisoquinolin-8-Amine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of this high-value intermediate for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.