Description

Peg5-Bis-(Ethyl Phosphonate) CAS NO 1446282-28-5 is a specialized bifunctional phosphonate derivative featuring a polyethylene glycol (PEG) spacer, designed for applications requiring controlled reactivity and solubility. This compound is valued for its ability to act as a versatile linker or functionalizing agent in advanced material synthesis and bioconjugation. It is particularly relevant for researchers and manufacturers in the pharmaceutical, biotech, and specialty polymer industries seeking to modify surfaces or create novel conjugates with precise properties.

Application

• As a bifunctional linker in the synthesis of targeted drug delivery systems and antibody-drug conjugates (ADCs).
• For the surface functionalization of nanoparticles, quantum dots, and other nanomaterials to impart hydrophilicity and specific reactivity.
• As a key intermediate in the development of PEGylated prodrugs and therapeutic agents to enhance solubility and pharmacokinetic profiles.
• In the creation of cross-linked hydrogels and smart polymers for biomedical and diagnostic applications.
• As a chelating agent precursor for metal ion binding in catalysis or imaging applications.
• For the modification of peptides, proteins, and oligonucleotides to introduce phosphonate groups for stability or targeting.
• In material science for the development of flame-retardant or anti-corrosion coatings where phosphonate chemistry is beneficial.

Basic Information

Product Name	Peg5-Bis-(Ethyl Phosphonate)
CAS No.	1446282-28-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bis(ethyl phosphonate)-PEG5; PEG-5 Bis(Ethyl Phosphonate); 1,11-Bis(diethylphosphono)-3,6,9-trioxaundecane; Diethyl (((2,5,8,11-tetraoxatridecane-1,13-diyl)bis(oxy))bis(ethane-2,1-diyl))bis(phosphonate); Ethylene glycol oligomer bis(ethyl phosphonate); Polyethylene glycol bis(diethylphosphonate) (n~5); Phosphonate-PEG5-Phosphonate; PEGylated bisphosphonate linker
EINECS	Contact for details

Quality Control

Our Peg5-Bis-(Ethyl Phosphonate) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere or in a controlled environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.