Description

Racemic-(3Ar,6S,6Ar)-tert-Butyl 6-Aminotetrahydro-2H-Furo[3,2-B]Pyrrole-4(5H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex fused furopyrrolidine scaffold. This compound is a critical chiral building block for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing innovative therapeutics, particularly in the areas of central nervous system (CNS) and antiviral drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of complex drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Integral in the development and scale-up processes for new active pharmaceutical ingredients, especially those targeting neurological pathways.
• Asymmetric Synthesis: Employed in the construction of stereochemically defined molecules due to its defined chiral centers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for methodological studies in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	Racemic-(3Ar,6S,6Ar)-tert-Butyl 6-Aminotetrahydro-2H-Furo[3,2-B]Pyrrole-4(5H)-Carboxylate
CAS No.	1445951-76-7
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	tert-Butyl 6-amino-2,3,3a,4,5,6a-hexahydrofuro[3,2-b]pyrrole-4-carboxylate; (±)-(3aR,6S,6aR)-tert-Butyl 6-aminohexahydro-2H-furo[3,2-b]pyrrole-4(5H)-carboxylate; 6-Amino-2,3,3a,4,5,6a-hexahydrofuro[3,2-b]pyrrole-4-carboxylic acid tert-butyl ester; Furo[3,2-b]pyrrole-4(5H)-carboxylic acid, 6-aminohexahydro-, 1,1-dimethylethyl ester, (3aR,6S,6aR)-; tert-Butyl (3aR,6S,6aR)-6-aminohexahydro-2H-furo[3,2-b]pyrrole-4(5H)-carboxylate (racemic); BOC-protected furopyrrolidine amine.
EINECS	Contact for details

Quality Control

Our production of Racemic-(3Ar,6S,6Ar)-tert-Butyl 6-Aminotetrahydro-2H-Furo[3,2-B]Pyrrole-4(5H)-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis, and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Racemic mixture
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.