Description

Racemic-(3As,6R,7R,7Ar)-2-(tert-Butoxycarbonyl)Octahydro-3A,6-Epoxyisoindole-7-Carboxylic Acid (Wx125292) is a sophisticated, high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering a rigid, fused bicyclic scaffold that is valuable for introducing specific stereochemistry and conformational constraints. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in areas requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, including central nervous system (CNS) drugs and other small molecule pharmaceuticals.
• Asymmetric Synthesis: Used as a starting material or intermediate in complex asymmetric synthesis routes to construct molecules with defined three-dimensional architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization to explore new chemical spaces and improve drug-like properties.
• Process Chemistry Development: Acts as a critical intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Academic & Industrial R&D: Utilized in chemical research for developing new synthetic methodologies and exploring novel heterocyclic chemistry.

Basic Information

Product Name	Racemic-(3As,6R,7R,7Ar)-2-(tert-Butoxycarbonyl)Octahydro-3A,6-Epoxyisoindole-7-Carboxylic Acid (Wx125292)
CAS No.	1445949-61-0
Molecular Formula	C14H21NO5
Molecular Weight	283.32 g/mol
Synonyms	(3aR,6R,7R,7aR)-2-[(tert-Butoxy)carbonyl]octahydro-3a,6-epoxyisoindole-7-carboxylic Acid; (±)-(3aR,6R,7R,7aR)-2-(tert-Butoxycarbonyl)octahydro-3a,6-epoxyisoindole-7-carboxylic Acid; WX-125292; WX125292; 2-Boc-octahydro-3a,6-epoxyisoindole-7-carboxylic acid; tert-Butyl 7-carboxyhexahydro-3a,6-epoxyisoindole-2(1H)-carboxylate; 1,2,3,3a,4,7,8,8a-Octahydro-3a,6-epoxyisoindole-7-carboxylic acid, 2-[(1,1-dimethylethoxy)carbonyl]-; Bicyclic proline derivative.
EINECS	Contact for details

Quality Control

Our Racemic-(3As,6R,7R,7Ar)-2-(tert-Butoxycarbonyl)Octahydro-3A,6-Epoxyisoindole-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical and chiral purity suitable for demanding pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Racemic mixture
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.