Description

5-Bromo-8-Chloro-1,2,3,4-Tetrahydroisoquinoline is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique halogenated tetrahydroisoquinoline scaffold makes it a critical intermediate for developing novel pharmacologically active compounds. This product is primarily targeted at research and development teams in the pharmaceutical, agrochemical, and material science industries seeking to create new molecules with specific biological or physical properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and other therapeutic small molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Chemical Biology & Probe Development: Employed as a scaffold for creating molecular probes and tool compounds to study biological pathways and protein function.
• Material Science Precursor: Acts as a building block for synthesizing specialized ligands, catalysts, and organic electronic materials.
• Academic & Contract Research: Utilized in university and CRO laboratories for method development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	5-Bromo-8-Chloro-1,2,3,4-Tetrahydroisoquinoline
CAS No.	1445948-16-2
Molecular Formula	C9H9BrClN
Molecular Weight	246.53 g/mol
Synonyms	5-Bromo-8-chloro-1,2,3,4-tetrahydroisoquinoline; 8-Chloro-5-bromo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-5-bromo-8-chloroisoquinoline; 5-Bromo-8-chloro-3,4-dihydro-1H-isoquinoline; 5-Bromo-8-chloro-THIQ; BCTHIQ
EINECS	Contact for details

Quality Control

Our 5-Bromo-8-Chloro-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.