Description

6-Bromo-5-Fluoro-1,2-Dihydroisoquinolin-1-One is a high-purity, advanced pharmaceutical intermediate designed for precision synthesis. This compound is a critical building block in modern medicinal chemistry, valued for its unique halogenated isoquinolinone scaffold that enables the development of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the discovery and production of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing fused heterocyclic compounds with potential biological activity.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and bioorganic chemistry.

Basic Information

Product Name	6-Bromo-5-Fluoro-1,2-Dihydroisoquinolin-1-One
CAS No.	1445564-00-0
Molecular Formula	C9H5BrFNO
Molecular Weight	242.05 g/mol
Synonyms	6-Bromo-5-fluoro-1,2-dihydroisoquinolin-1-one; 6-Bromo-5-fluoro-1H-isoquinolin-1-one; 1H-Isoquinolin-1-one, 6-bromo-5-fluoro-1,2-dihydro-; 1445564-00-0; 6-Br-5-F-1,2-dihydroisoquinolin-1-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Fluoro-1,2-Dihydroisoquinolin-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with client specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.