Description

Methanone, [3-(Chloromethyl)-2,4,6-Trimethylphenyl](Diphenylphosphinyl)- is a specialized organophosphorus compound that serves as a high-value intermediate in advanced chemical synthesis. Its molecular architecture, featuring both phosphinyl and chloromethyl functional groups, makes it a critical building block for constructing complex molecules with tailored properties. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical sectors, where it is utilized in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a sophisticated precursor for creating chiral phosphine ligands used in asymmetric catalysis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Useful for modifying biomolecules and developing activity-based probes for enzyme studies.

Basic Information

Item	Detail
Product Name	Methanone, [3-(Chloromethyl)-2,4,6-Trimethylphenyl](Diphenylphosphinyl)-
CAS No.	1444690-54-3
Molecular Formula	C23H22ClO2P
Molecular Weight	396.84 g/mol
Synonyms	[3-(Chloromethyl)-2,4,6-trimethylphenyl](diphenylphosphinyl)methanone; (2,4,6-Trimethyl-3-(chloromethyl)phenyl)(diphenylphosphine oxide) ketone; Diphenylphosphinyl(3-chloromethyl-2,4,6-trimethylphenyl)methanone; Phosphine oxide, P,P-diphenyl-P'-[3-(chloromethyl)-2,4,6-trimethylphenyl] ketone; CAS 1444690-54-3
EINECS	Contact for details

Quality Control

Every batch of Methanone, [3-(Chloromethyl)-2,4,6-Trimethylphenyl](Diphenylphosphinyl)- is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.