Description

(1S)-1-(1,3-Thiazol-5-Yl)Ethan-1-Ol Hydrochloride is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. Its core value lies in providing a critical, enantiomerically pure building block for the development of novel active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the production of advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly in antiviral, anti-inflammatory, or central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used as a building block for creating enantiomerically pure active ingredients in advanced pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in academic and industrial research focused on developing new chiral catalysts.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and target engagement, leveraging the thiazole moiety for potential binding interactions.
• Process Chemistry Development: Employed in scaling up synthetic routes for APIs where the (1S) enantiomer is required for optimal biological activity and regulatory approval.

Basic Information

Product Name	(1S)-1-(1,3-Thiazol-5-Yl)Ethan-1-Ol Hydrochloride
CAS No.	1443931-85-8
Molecular Formula	C5H8ClNOS
Molecular Weight	165.64 g/mol
Synonyms	(S)-1-(Thiazol-5-yl)ethanol hydrochloride; (1S)-1-(1,3-Thiazol-5-yl)ethan-1-ol hydrochloride; (S)-5-(1-Hydroxyethyl)thiazole hydrochloride; 5-[(1S)-1-Hydroxyethyl]-1,3-thiazole hydrochloride; (S)-α-Methyl-5-thiazolemethanol hydrochloride; L-1-(5-Thiazolyl)ethanol hydrochloride; (1S)-1-(Thiazol-5-yl)ethyl alcohol hydrochloride
EINECS	Contact for details

Quality Control

Our (1S)-1-(1,3-Thiazol-5-Yl)Ethan-1-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.