Description

2,2-Difluoro-2-Thiophen-2-Yl-Ethanol is a specialized fluorinated thiophene derivative, a high-value building block in advanced organic synthesis. Its unique structure, featuring both a thiophene heterocycle and a difluoroethanol moiety, makes it a critical intermediate for creating novel compounds with tailored properties. This product is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorine-containing electronic materials used in displays and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated into specialty polymers to impart specific characteristics such as altered solubility, thermal stability, or surface properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new fluorination chemistry and heterocyclic compound libraries.
• Ligand & Catalyst Development: Potential use in synthesizing novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2,2-Difluoro-2-Thiophen-2-Yl-Ethanol
CAS No.	1443500-45-5
Molecular Formula	C6H6F2OS
Molecular Weight	164.17 g/mol
Synonyms	2-(2,2-Difluoro-2-hydroxyethyl)thiophene; 2-(Thiophen-2-yl)-2,2-difluoroethanol; α,α-Difluoro-2-thiopheneethanol; 2-Thienyl-2,2-difluoroethanol; 2,2-Difluoro-2-(2-thienyl)ethanol; 2-(2,2-Difluoroethoxy)thiophene (incorrect but common search variant); DFTE (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 2,2-Difluoro-2-Thiophen-2-Yl-Ethanol is produced and tested under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.