Description

6-Chloro-1H-Benzimidazole-2-Carboxylic Acid Monohydrate is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its functionalized benzimidazole core, which is essential for constructing molecules with specific biological and material properties. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in developing advanced fungicides, herbicides, and plant growth regulators due to its bioactive heterocyclic structure.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Organic Electronic Materials: Potential building block for electron-transport materials or organic semiconductors in OLED and photovoltaic research.
• Bioconjugation Chemistry: The carboxylic acid group enables coupling to biomolecules for probe or conjugate development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	6-Chloro-1H-Benzimidazole-2-Carboxylic Acid Monohydrate
CAS No.	1443425-14-6
Molecular Formula	C8H5ClN2O2 • H2O
Molecular Weight	216.60 g/mol (Anhydrous basis: 198.59 g/mol)
Synonyms	6-Chloro-1H-benzimidazole-2-carboxylic acid hydrate; 2-Carboxy-6-chlorobenzimidazole monohydrate; 6-Chloro-1H-benzo[d]imidazole-2-carboxylic acid monohydrate; 6-Chloro-2-benzimidazolecarboxylic acid hydrate; 6-Chloro-2-carboxybenzimidazole; 1443425-14-6; 6-Chloro-1H-benzimidazole-2-carboxylic acid water (1:1)
EINECS	Contact for details

Quality Control

Our 6-Chloro-1H-Benzimidazole-2-Carboxylic Acid Monohydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	7.0% - 9.0% (Theoretical: ~8.3%)
Related Substances (HPLC)	Total impurities ≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.