Description

6-Chloro-2,3,4,9-Tetrahydro-1H-Carbazol-1-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1443424-91-6. This compound is a critical building block in modern medicinal chemistry, valued for its role in synthesizing complex heterocyclic molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel carbazole-based drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex polycyclic frameworks in academic and industrial R&D.
• Biochemical Research: Potential use in developing enzyme inhibitors or receptor ligands for biochemical assays.
• Reference Standard: Sourced for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	6-Chloro-2,3,4,9-Tetrahydro-1H-Carbazol-1-Amine Hydrochloride
CAS No.	1443424-91-6
Molecular Formula	C12H14Cl2N2
Molecular Weight	257.16 g/mol
Synonyms	6-Chloro-1,2,3,4-tetrahydro-9H-carbazol-1-amine hydrochloride; 1-Amino-6-chloro-1,2,3,4-tetrahydrocarbazole hydrochloride; 6-Chloro-2,3,4,9-tetrahydro-1H-carbazol-1-amine HCl; 1443424-91-6; 6-Chloro-THCA HCl; 6-Cl-THCA-Amine HCl
EINECS	Contact for details

Quality Control

Our 6-Chloro-2,3,4,9-Tetrahydro-1H-Carbazol-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.