Description

4-[3-[4-Cyano-3-(Trifluoromethyl)Phenyl]-5,5-Dimethyl-4-Oxo-2-Thioxo-1-Imidazolidinyl]-2-Fluoro-n-(Methyl-D3)Benzamide is a high-purity, deuterated pharmaceutical intermediate designed for advanced research and development. This compound is critical for metabolic and pharmacokinetic studies, offering enhanced stability and traceability in analytical applications. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in the development of novel therapeutic agents, particularly in the fields of oncology and endocrinology.

Application

• Deuterated Internal Standard for precise quantification in LC-MS and GC-MS analysis.
• Metabolic Pathway Tracing in drug discovery and development studies.
• Pharmaceutical Intermediate for the synthesis of deuterated drug candidates.
• Reference Standard for quality control and method validation in analytical laboratories.
• Biochemical Research involving enzyme inhibition and receptor binding assays.
• Preclinical Development for investigating the pharmacokinetics (PK) and pharmacodynamics (PD) of new chemical entities.

Basic Information

Product Name	4-[3-[4-Cyano-3-(Trifluoromethyl)Phenyl]-5,5-Dimethyl-4-Oxo-2-Thioxo-1-Imidazolidinyl]-2-Fluoro-n-(Methyl-D3)Benzamide
CAS No.	1443331-82-5
Molecular Formula	C21H15D3F4N4O2S
Molecular Weight	469.45 g/mol
Synonyms	N-(Methyl-d3)-4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzamide; Bicalutamide Methyl-d3; Bicalutamide-d3; 2-Fluoro-4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-N-(trideuteriomethyl)benzamide; CAS 1443331-82-5; Deuterated Bicalutamide Derivative; Bicalutamide Impurity D3
EINECS	Contact for details

Quality Control

Every batch of our 4-[3-[4-Cyano-3-(Trifluoromethyl)Phenyl]-5,5-Dimethyl-4-Oxo-2-Thioxo-1-Imidazolidinyl]-2-Fluoro-n-(Methyl-D3)Benzamide is manufactured and tested under strict quality management systems. We guarantee high chemical purity and isotopic enrichment suitable for sensitive analytical applications. Comprehensive testing includes assay, isotopic purity (D-content), and identification by spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with your research or quality specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.