Description

4-Iodo-1-Methyl-1H-Pyrazol-5-Amine is a high-value, halogenated pyrazole derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and an amine group, makes it an indispensable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used to create novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for advanced organic electronic materials and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The iodine atom facilitates important palladium-catalyzed reactions like Suzuki-Miyaura and Buchwald-Hartwig couplings.

Basic Information

Product Name	4-Iodo-1-Methyl-1H-Pyrazol-5-Amine
CAS No.	1443278-79-2
Molecular Formula	C4H6IN3
Molecular Weight	223.01 g/mol
Synonyms	1-Methyl-4-iodo-1H-pyrazol-5-amine; 5-Amino-1-methyl-4-iodopyrazole; 4-Iodo-1-methyl-5-aminopyrazole; 1-Methyl-4-iodopyrazol-5-ylamine; 4-Iodo-1-methyl-1H-pyrazol-5-ylamine; 1443278-79-2
EINECS	Contact for details

Quality Control

Our 4-Iodo-1-Methyl-1H-Pyrazol-5-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles for pharmaceutical-grade intermediates, and specifications can be customized to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.