Description

2-tert-Butoxycarbonyloxy-Indole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected indole derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its primary value lies in providing a versatile and reactive scaffold for constructing complex heterocyclic molecules, particularly in the pharmaceutical sector. This compound is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel indole-based drug candidates, including kinase inhibitors and serotonin receptor modulators.
• Agrochemical Research: Used in the development of new herbicides and plant growth regulators that leverage the indole core structure.
• Organic Synthesis Reagent: Serves as a protected precursor for introducing the indole moiety into more complex molecular frameworks under controlled conditions.
• Material Science: Potential monomer or intermediate for creating specialized polymers and organic electronic materials.
• Academic & R&D: A valuable tool for methodological development and exploring new chemical reactions in university and industrial research laboratories.

Basic Information

Product Name	2-tert-Butoxycarbonyloxy-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1440526-59-9
Molecular Formula	C18H23NO5
Molecular Weight	333.38 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 2-[[(1,1-dimethylethoxy)carbonyl]oxy]-, 1,1-dimethylethyl ester; tert-Butyl 2-((tert-butoxycarbonyl)oxy)-1H-indole-1-carboxylate; 2-BocO-Indole-1-COOtBu; 2-(Boc-oxy)indole-1-carboxylic acid tert-butyl ester; 1-Boc-2-BocO-indole; Di-Boc protected 2-hydroxyindole; 2-Hydroxyindole Di-Boc Derivative
EINECS	Contact for details

Quality Control

Our 2-tert-Butoxycarbonyloxy-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.