Description

(6-Trifluoromethyl-Benzothiazol-2-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its benzothiazole core and trifluoromethyl group. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily needed by R&D laboratories, custom synthesis firms, and pharmaceutical manufacturers engaged in the development of new chemical entities, especially those exploring the pharmacological benefits of fluorinated heterocycles.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those incorporating the benzothiazole scaffold for potential activity in oncology, neurology, and anti-infective therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop compounds with improved potency, selectivity, and metabolic stability.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new generation pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Potential use in the development of specialty chemicals, dyes, or functional materials that require fluorinated aromatic heterocycles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of targeted molecules on a commercial scale under cGMP conditions.

Basic Information

Product Name	(6-Trifluoromethyl-Benzothiazol-2-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1440526-38-4
Molecular Formula	C13H13F3N2O2S
Molecular Weight	318.31 g/mol
Synonyms	tert-Butyl N-(6-(trifluoromethyl)-1,3-benzothiazol-2-yl)carbamate; 2-(((tert-Butoxy)carbonyl)amino)-6-(trifluoromethyl)benzothiazole; Boc-Protected 2-Amino-6-trifluoromethylbenzothiazole; N-Boc-2-Amino-6-(trifluoromethyl)benzothiazole; tert-Butyl (6-(trifluoromethyl)benzo[d]thiazol-2-yl)carbamate; 2-((tert-Butoxycarbonyl)amino)-6-(trifluoromethyl)benzothiazole; CAS 1440526-38-4
EINECS	Contact for details

Quality Control

Our (6-Trifluoromethyl-Benzothiazol-2-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.