Description

5-Chloro-3,3-Dimethylisoindolin-1-One is a high-value pharmaceutical intermediate and versatile organic building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and advanced material science. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides with specific modes of action.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in advanced display technologies.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent to impart specific properties to high-performance polymers.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemistry research, enabling novel ring-forming reactions and structural diversification.

Basic Information

Product Name	5-Chloro-3,3-Dimethylisoindolin-1-One
CAS No.	1440519-63-0
Molecular Formula	C10H10ClNO
Molecular Weight	195.65 g/mol
Synonyms	5-Chloro-3,3-dimethyl-2,3-dihydro-1H-isoindol-1-one; 5-Chloro-3,3-dimethylisoindolinone; 1H-Isoindol-1-one, 5-chloro-3,3-dihydro-3,3-dimethyl-; 1440519-63-0; 5-Chloro-3,3-dimethyl-1-isoindolinone; 3,3-Dimethyl-5-chloroisoindolin-1-one
EINECS	Contact for details

Quality Control

Our 5-Chloro-3,3-Dimethylisoindolin-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.