Description

[5-(Trifluoromethyl)-1,3-Thiazol-2-Yl]Methanol is a high-value fluorinated thiazole derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in the trifluoromethyl group, which imparts unique physicochemical properties essential for developing advanced materials and bioactive compounds. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability and lipophilicity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides, herbicides, and fungicides, leveraging the CF3 group for improved biological activity and environmental profile.
• Material Science Research: Serves as a precursor for specialty chemicals, liquid crystals, and advanced polymers where fluorine incorporation is desired for thermal stability and chemical resistance.
• Chemical Biology & Probe Development: Employed in creating molecular probes and biochemical tools for studying enzyme mechanisms and cellular processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	[5-(Trifluoromethyl)-1,3-Thiazol-2-Yl]Methanol
CAS No.	1434142-11-6
Molecular Formula	C5H4F3NOS
Molecular Weight	183.15 g/mol
Synonyms	2-(Hydroxymethyl)-5-(trifluoromethyl)thiazole; (5-Trifluoromethyl-1,3-thiazol-2-yl)methanol; 5-(Trifluoromethyl)-2-thiazolemethanol; 2-Thiazolemethanol, 5-(trifluoromethyl)-; 5-Trifluoromethylthiazole-2-methanol; (5-(Trifluoromethyl)thiazol-2-yl)methanol
EINECS	Contact for details

Quality Control

Our [5-(Trifluoromethyl)-1,3-Thiazol-2-Yl]Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines for advanced intermediates, ensuring traceability and documentation suitable for regulated industry use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.