Description

Methyl 3-Bromo-2-Methyl-2H-Indazole-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 1434142-10-5. This compound is a critical building block in modern medicinal chemistry, valued for its functionalized indazole core which enables the synthesis of targeted bioactive molecules. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile bromo and ester functional groups.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules.
• Agrochemical Research: Potential application in the discovery of new active ingredients for crop protection.

Basic Information

Product Name	Methyl 3-Bromo-2-Methyl-2H-Indazole-6-Carboxylate
CAS No.	1434142-10-5
Molecular Formula	C11H11BrN2O2
Molecular Weight	283.12 g/mol
Synonyms	3-Bromo-2-methyl-2H-indazole-6-carboxylic acid methyl ester; Methyl 3-bromo-2-methylindazole-6-carboxylate; 6-(Methoxycarbonyl)-2-methyl-2H-indazol-3-yl bromide; 1434142-10-5; 3-Bromo-2-methyl-1H-indazole-6-carboxylic acid methyl ester (tautomer); MBMI-6-COOMe
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Bromo-2-Methyl-2H-Indazole-6-Carboxylate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with the high-purity standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile data is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.