Description

4-Bromo-2-(4-Pyridinylcarbonyl)-3-Thiophenecarboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring bromine, pyridine, and thiophene moieties, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs).
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Academic & R&D: A valuable reagent for methodological studies in cross-coupling reactions and heterocyclic chemistry.
• Custom Synthesis: Provides a versatile starting point for contract research organizations (CROs) and CDMOs engaged in bespoke chemical manufacturing.

Basic Information

Product Name	4-Bromo-2-(4-Pyridinylcarbonyl)-3-Thiophenecarboxylic Acid
CAS No.	1433203-86-1
Molecular Formula	C11H6BrNO3S
Molecular Weight	312.14 g/mol
Synonyms	4-Bromo-2-(pyridine-4-carbonyl)thiophene-3-carboxylic acid; 4-Bromo-2-(4-pyridoyl)-3-thiophenecarboxylic acid; 3-Thiophenecarboxylic acid, 4-bromo-2-(4-pyridinylcarbonyl)-; 4-Bromo-2-(isonicotinoyl)thiophene-3-carboxylic acid; 4-Pyridinecarboxylic acid, 4-bromo-2-(3-thienylcarbonyl)- derivative; 1433203-86-1; Building block 1433203-86-1
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(4-Pyridinylcarbonyl)-3-Thiophenecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory requirements for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled and stored away from strong acids and organic solvents as indicated. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.