Description

5-Aminomethyl-7-Azaindole Hydrochloride is a high-purity, heterocyclic organic building block essential for advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of complex molecules, particularly for kinase inhibitors and other targeted therapeutic agents. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries to accelerate drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Process Chemistry: Serves as a building block in the scale-up and route development for active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.

Basic Information

Item	Detail
Product Name	5-Aminomethyl-7-Azaindole Hydrochloride
CAS No.	1432754-52-3
Molecular Formula	C8H10N3Cl
Molecular Weight	183.64 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridine-5-methanamine, hydrochloride; 7-Azaindole-5-methylamine hydrochloride; 5-(Aminomethyl)-1H-pyrrolo[2,3-b]pyridine hydrochloride; 5-(Aminomethyl)-7-azaindole HCl; 5-Aminomethyl-1H-pyrrolo[2,3-b]pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Aminomethyl-7-Azaindole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF for moisture content, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.