Description

6-Methyl-2,3,4,9-Tetrahydro-1H-Carbazol-3-One is a high-purity, advanced pharmaceutical intermediate belonging to the carbazole alkaloid class. This compound is a critical building block in the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the design of new chemical entities (NCEs).
• Organic Synthesis Building Block: Used in multi-step synthesis for constructing complex heterocyclic compounds and natural product analogs.
• Reference Standard: Employed as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Biochemical Research: Investigated for its potential biological activity and interactions with various enzymes and receptors in preclinical studies.

Basic Information

Product Name	6-Methyl-2,3,4,9-Tetrahydro-1H-Carbazol-3-One
CAS No.	1432682-04-6
Molecular Formula	C₁₃H₁₅NO
Molecular Weight	201.27 g/mol
Synonyms	6-Methyl-1,2,3,4-tetrahydro-9H-carbazol-3-one; 6-Methyl-2,3,4,9-tetrahydro-1H-carbazol-3-one; 6-Methyl-1,2,3,4-tetrahydrocarbazol-3-one; 3H-Carbazol-3-one, 2,3,4,9-tetrahydro-6-methyl-; 6-Methyl-2,3,4,9-tetrahydrocarbazol-3-one; 6-Methyltetrahydrocarbazol-3-one
EINECS	Contact for details

Quality Control

Our 6-Methyl-2,3,4,9-Tetrahydro-1H-Carbazol-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.