Description

2-[5-(Trifluoromethyl)Thiophen-2-Yl]Ethan-1-Amine Hydrochloride is a high-purity organic building block featuring a thiophene core functionalized with a trifluoromethyl group and an ethylamine hydrochloride side chain. This compound matters as a critical intermediate for medicinal chemistry and agrochemical research, enabling the synthesis of novel molecules with enhanced metabolic stability and bioavailability. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing active ingredients for therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a precursor in developing advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene and trifluoromethyl motifs.
• Material Science: Used in the research and development of specialty polymers and organic electronic materials due to its conjugated thiophene structure.
• Chemical Biology & Proteomics: Employed as a linker or functional handle in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	2-[5-(Trifluoromethyl)Thiophen-2-Yl]Ethan-1-Amine Hydrochloride
CAS No.	1432679-31-6
Molecular Formula	C7H9ClF3NS
Molecular Weight	231.66 g/mol
Synonyms	2-(5-(Trifluoromethyl)thiophen-2-yl)ethan-1-amine hydrochloride; 2-(5-(Trifluoromethyl)-2-thienyl)ethylamine hydrochloride; 2-[5-(Trifluoromethyl)-2-thienyl]ethylamine HCl; 5-(Trifluoromethyl)thiophene-2-ethylamine hydrochloride; 2-(5-Trifluoromethylthiophen-2-yl)ethylamine hydrochloride; 2-Aminoethyl-5-trifluoromethylthiophene hydrochloride; 2-(5-(Trifluoromethyl)thiophen-2-yl)ethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-[5-(Trifluoromethyl)Thiophen-2-Yl]Ethan-1-Amine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with exacting industry standards. Certificates of Analysis (COA) with full batch traceability are provided to guarantee supply reliability and product consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.