Description

4-Bromo-6-(Pentafluorothio)-1H-Benzimidazole, also known as 4-Bromo-6-(Pentafluorosulphanyl)-1H-Benzimidazole, is a high-value, fluorinated benzimidazole derivative characterized by its unique pentafluorothio/sulphanyl functional group. This compound is a critical advanced pharmaceutical intermediate and a versatile building block in modern organic synthesis, enabling the introduction of lipophilic and electron-withdrawing motifs. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, antiviral, and CNS therapeutic areas.
• Agrochemical Research: Used to develop new generations of herbicides, fungicides, and insecticides with enhanced activity and environmental profiles.
• Material Science Building Block: Incorporated into advanced polymers, liquid crystals, and electronic materials to modify thermal stability and electronic properties.
• Ligand Synthesis: Serves as a scaffold for creating specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: An essential compound for studying the effects of the pentafluorosulphanyl group in medicinal and materials chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules for client-specific R&D programs.

Basic Information

Item	Detail
Product Name	4-Bromo-6-(Pentafluorothio)-1H-Benzimidazole, 4-Bromo-6-(Pentafluorosulphanyl)-1H-Benzimidazole
CAS No.	1432075-84-7
Molecular Formula	C7H2BrF5N2S
Molecular Weight	321.07 g/mol
Synonyms	4-Bromo-6-(pentafluoro-λ6-sulfanyl)-1H-benzimidazole; 4-Bromo-6-(pentafluorothio)benzimidazole; 4-Bromo-6-SF5-1H-benzimidazole; 6-(Pentafluorosulfanyl)-4-bromo-1H-benzimidazole; 1H-Benzimidazole, 4-bromo-6-(pentafluorothio)-; Benzimidazole, 4-bromo-6-(pentafluorosulfanyl)-; CAS 1432075-84-7
EINECS	Contact for details

Quality Control

Every batch of our 4-Bromo-6-(Pentafluorothio)-1H-Benzimidazole is manufactured under strict quality management systems. Our products undergo rigorous quality testing including HPLC, NMR, and MS to ensure identity, purity, and consistency, meeting the exacting standards required for research and development. Certificates of Analysis (COA) with full analytical data are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.