Description

5-Bromo-3-Fluoro-Thiophene-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique molecular architecture, which allows for precise structural modifications in the development of novel active compounds. This intermediate is critically needed by R&D and production teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Serves as a crucial precursor in the design and synthesis of next-generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Used in the synthesis of specialized monomers and polymers, including conductive polymers and organic electronic materials.
• Ligand and Catalyst Development: Acts as a starting material for creating complex ligands used in transition metal catalysis and asymmetric synthesis.
• Chemical Biology Probes: Employed in the construction of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis services catering to specialized R&D projects.

Basic Information

Product Name	5-Bromo-3-Fluoro-Thiophene-2-Carboxylic Acid
CAS No.	1432060-81-5
Molecular Formula	C5H2BrFO2S
Molecular Weight	225.04 g/mol
Synonyms	2-Bromo-5-fluoro-3-thiophenecarboxylic acid; 3-Thiophenecarboxylic acid, 5-bromo-3-fluoro-; 5-Bromo-3-fluorothiophene-2-carboxylic acid; 5-Bromo-3-fluoro-2-thiophenecarboxylic acid; 2-Carboxy-5-bromo-3-fluorothiophene; 3-Fluoro-5-bromothiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Fluoro-Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch and provided upon request, detailing all relevant specifications to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.