Description

5-Bromo-4,4-Dimethyl-3,4-Dihydroisoquinoline-1(2H)-One is a high-value, synthetically versatile brominated isoquinoline derivative. This compound serves as a critical pharmaceutical intermediate and organic building block for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce functionalized isoquinoline scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used as a building block for developing new active ingredients in crop protection and pesticide formulations.
• Organic Synthesis: Serves as a versatile electrophile or coupling partner in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for introducing the bromo-isoquinoline moiety.
• Material Science: Potential monomer or precursor for creating specialized polymers, ligands for catalysis, or organic electronic materials.
• Chemical Biology: Useful for synthesizing molecular probes and tool compounds for studying biological pathways and protein function.

Basic Information

Product Name	5-Bromo-4,4-Dimethyl-3,4-Dihydroisoquinoline-1(2H)-One
CAS No.	1430563-79-3
Molecular Formula	C₁₁H₁₂BrNO
Molecular Weight	254.12 g/mol
Synonyms	5-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroisoquinolin-1-one; 4,4-Dimethyl-5-bromo-3,4-dihydro-1(2H)-isoquinolinone; 5-Bromo-4,4-dimethyl-3,4-dihydro-1H-isoquinolin-1-one; 1(2H)-Isoquinolinone, 5-bromo-4,4-dimethyl-3,4-dihydro-; 5-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline-1-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-4,4-Dimethyl-3,4-Dihydroisoquinoline-1(2H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.