Description

5-Chloro-1-(Methyl-D3)-4-Nitro-1H-Pyrazole CAS NO 1428577-87-0 is a deuterated pyrazole derivative, a high-value building block for advanced chemical synthesis. This compound is specifically engineered for applications requiring isotopic labeling, offering enhanced metabolic stability and traceability in research. It is primarily utilized by pharmaceutical and agrochemical R&D teams developing novel active ingredients, as well as by analytical laboratories for use as an internal standard in mass spectrometry.

Application

• Pharmaceutical Intermediate: A key deuterated synthon in the research and development of new drug candidates, particularly for improving pharmacokinetic profiles.
• Agrochemical Research: Used in the synthesis of novel, isotopically labeled pesticides and herbicides to study environmental fate and metabolic pathways.
• Metabolite Tracing: Serves as a stable isotope-labeled precursor in metabolic studies and biochemical research.
• Analytical Standard: Employed as a high-purity internal standard or reference material in LC-MS and GC-MS analysis for accurate quantification.
• Material Science: A potential building block for advanced organic materials and ligands in catalytic systems.

Basic Information

Product Name	5-Chloro-1-(Methyl-D3)-4-Nitro-1H-Pyrazole
CAS No.	1428577-87-0
Molecular Formula	C4H2D3ClN3O2
Molecular Weight	162.58 g/mol (approx.)
Synonyms	1-(Trideuteriomethyl)-5-chloro-4-nitro-1H-pyrazole; 5-Chloro-1-(methyl-d3)-4-nitro-1H-pyrazole; 5-Chloro-4-nitro-1-(trideuteriomethyl)pyrazole; Deuterated 5-Chloro-1-methyl-4-nitropyrazole; (Methyl-d3)-5-chloro-4-nitropyrazole; 5-Chloro-4-nitro-1H-pyrazole-1-(methyl-d3); 1H-Pyrazole, 5-chloro-1-(methyl-d3)-4-nitro-
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-(Methyl-D3)-4-Nitro-1H-Pyrazole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C), HPLC, and MS, to confirm identity, chemical purity, and isotopic enrichment. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (D3)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.