Description

Methyl 3-Amino-6-(5-Methyl-2-Furyl)-4-Oxo-4,5,6,7-Tetrahydro-1H-Indole-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1428139-54-1. This compound is a critical building block in modern organic synthesis, valued for its complex fused-ring structure that serves as a key precursor in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of new therapeutic agents, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct intricate molecular architectures due to its reactive amino and ester functional groups.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery pipelines.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and scale-up activities.
• Academic Research: Utilized in university and institutional laboratories for methodological development and the study of novel heterocyclic reactions.
• Agrochemical Intermediate: Potential application as a precursor in the synthesis of novel, high-value crop protection agents.

Basic Information

Item	Detail
Product Name	Methyl 3-Amino-6-(5-Methyl-2-Furyl)-4-Oxo-4,5,6,7-Tetrahydro-1H-Indole-2-Carboxylate
CAS No.	1428139-54-1
Molecular Formula	C16H16N2O4
Molecular Weight	300.31 g/mol
Synonyms	Methyl 3-amino-6-(5-methylfuran-2-yl)-4-oxo-1,4,5,6,7,8-hexahydroindole-2-carboxylate; 3-Amino-6-(5-methyl-2-furyl)-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylic acid methyl ester; 1H-Indole-2-carboxylic acid, 3-amino-6-(5-methyl-2-furanyl)-4,5,6,7-tetrahydro-4-oxo-, methyl ester; 1428139-54-1; Methyl 3-amino-6-(5-methyl-2-furyl)-4-oxo-1,4,5,6,7,8-hexahydroindole-2-carboxylate; 6-(5-Methylfuran-2-yl)-4-oxo-3-amino-4,5,6,7-tetrahydro-1H-indole-2-carboxylic acid methyl ester.
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Amino-6-(5-Methyl-2-Furyl)-4-Oxo-4,5,6,7-Tetrahydro-1H-Indole-2-Carboxylate is manufactured under a strict quality management system and undergoes comprehensive analytical testing. Our products are guaranteed to meet the high-purity standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.