Description

3-Acetyl-5-Bromo-4-Methoxy-7-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its unique azaindole scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and antiviral fields.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other targeted small molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable functional groups.
• Chemical Biology Probes: Serves as a core structure for developing selective enzyme inhibitors and cellular probes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Used in university and institutional labs for fundamental research on heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	3-Acetyl-5-Bromo-4-Methoxy-7-Azaindole
CAS No.	1427504-73-1
Molecular Formula	C12H11BrN2O2
Molecular Weight	295.14 g/mol
Synonyms	5-Bromo-4-methoxy-7-azaindol-3-yl methyl ketone; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-4-methoxy-3-acetyl-; 3-Acetyl-5-bromo-4-methoxy-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-3-acetyl-4-methoxy-7-azaindole; 5-Bromo-4-methoxy-3-acetyl-1H-pyrrolo[2,3-b]pyridine; 3-Acetyl-5-bromo-4-methoxy-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Acetyl-5-Bromo-4-Methoxy-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring material integrity for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to prevent degradation. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.