Description

3-Acetyl-5-Bromo-4-Methyl-7-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its unique azaindole scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel kinase inhibitors and other targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting protein kinases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic programs.
• Chemical Biology Probes: Serves as a core structure for developing selective molecular probes to study biological pathways.
• Contract Manufacturing: Supplied to CDMOs for the scale-up and cGMP production of investigational and commercial drugs.
• Academic Research: Employed in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	3-Acetyl-5-Bromo-4-Methyl-7-Azaindole
CAS No.	1427503-08-9
Molecular Formula	C12H11BrN2O
Molecular Weight	279.14 g/mol
Synonyms	5-Bromo-4-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl ethanone; 1-(5-Bromo-4-methyl-7-azaindol-3-yl)ethanone; 3-Acetyl-5-bromo-4-methyl-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-4-methyl-3-acetyl-7-azaindole; 3-Acetyl-5-bromo-4-methyl-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-4-methyl-7-azaindol-3-yl methyl ketone
EINECS	Contact for details

Quality Control

Our 3-Acetyl-5-Bromo-4-Methyl-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 standards, and we support our clients with the documentation required for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.