Description

Methyl 7-Fluoro-1H-Indazole-5-Carboxylate is a high-purity fluorinated indazole derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a versatile building block for constructing complex molecules in modern drug discovery programs. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the bioactivity of the fluorinated indazole scaffold.
• Material Science: Acts as a precursor for specialty chemicals and functional materials, including liquid crystals and organic semiconductors.
• Academic & Contract Research: Serves as a standard or building block in medicinal chemistry and organic synthesis research within universities and CROs (Contract Research Organizations).

Basic Information

Product Name	Methyl 7-Fluoro-1H-Indazole-5-Carboxylate
CAS No.	1427431-00-2
Molecular Formula	C9H7FN2O2
Molecular Weight	194.16 g/mol
Synonyms	7-Fluoro-1H-indazole-5-carboxylic acid methyl ester; Methyl 7-fluoro-1H-indazole-5-carboxylate; 1H-Indazole-5-carboxylic acid, 7-fluoro-, methyl ester; 5-Methoxycarbonyl-7-fluoro-1H-indazole; 7-Fluoro-1H-indazole-5-methyl carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 7-Fluoro-1H-Indazole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.