Description

(2-Trifluoromethyl-Thiazol-4-Yl)-Acetonitrile is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique structure, featuring both a thiazole ring and a trifluoromethyl group, enables the introduction of critical properties like metabolic stability and enhanced lipophilicity into target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and scale-up of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for functionalized molecules used in organic electronics and specialty polymers.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	(2-Trifluoromethyl-Thiazol-4-Yl)-Acetonitrile
CAS No.	1427195-13-8
Molecular Formula	C6H3F3N2S
Molecular Weight	192.16 g/mol
Synonyms	4-(Cyanomethyl)-2-(trifluoromethyl)thiazole; 2-(Trifluoromethyl)-4-thiazoleacetonitrile; (2-(Trifluoromethyl)-1,3-thiazol-4-yl)acetonitrile; 2-(Trifluoromethyl)thiazole-4-acetonitrile; 4-Thiazoleacetonitrile, 2-(trifluoromethyl)-; (2-Trifluoromethyl-4-thiazolyl)acetonitrile
EINECS	Contact for details

Quality Control

Every batch of (2-Trifluoromethyl-Thiazol-4-Yl)-Acetonitrile is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.