Description

Ethyl 5-Amino-1-(2,2-Dimethylpropyl)-4-Iodo-Pyrazole-3-Carboxylate is a high-purity, functionalized pyrazole derivative designed for advanced chemical synthesis. This compound serves as a critical building block in pharmaceutical research and development, offering a versatile scaffold for creating novel active ingredients. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and protein-ligand interactions in biological systems.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers with unique electronic or thermal properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity advanced intermediates.

Basic Information

Product Name	Ethyl 5-Amino-1-(2,2-Dimethylpropyl)-4-Iodo-Pyrazole-3-Carboxylate
CAS No.	1427021-75-7
Molecular Formula	C11H18IN3O2
Molecular Weight	351.19 g/mol
Synonyms	5-Amino-1-neopentyl-4-iodo-1H-pyrazole-3-carboxylic acid ethyl ester; Ethyl 5-amino-1-neopentyl-4-iodo-1H-pyrazole-3-carboxylate; 1H-Pyrazole-3-carboxylic acid, 5-amino-1-(2,2-dimethylpropyl)-4-iodo-, ethyl ester; 4-Iodo-1-neopentyl-1H-pyrazole-3,5-diamine 3-carboxylate; AI3-53185; BRN 27503573; ZINC000103092905
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-Amino-1-(2,2-Dimethylpropyl)-4-Iodo-Pyrazole-3-Carboxylate is manufactured and tested under a strict quality management system. We ensure compliance with ICH Q7 guidelines for active pharmaceutical ingredients (APIs) and intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.