Description

Bcn-Osu CAS NO 1426827-79-3 is a specialized chemical building block, specifically an activated ester derivative, widely utilized in advanced organic synthesis and bioconjugation. Its primary value lies in enabling efficient and selective amide bond formation under mild conditions, which is critical for constructing complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life sciences sectors developing novel active compounds and diagnostic probes.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs requiring selective amide coupling.
• Peptide Synthesis: Used as a coupling agent for the efficient formation of peptide bonds in solid-phase and solution-phase peptide chemistry.
• Bioconjugation & Labeling: Facilitates the attachment of fluorescent dyes, biotin, or other functional tags to proteins, antibodies, and oligonucleotides for diagnostic and research applications.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating functionalized polymers with specific amide linkages.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Integral for synthesizing activity-based probes and other tools used to study enzyme function and biological pathways.

Basic Information

Product Name	Bcn-Osu
CAS No.	1426827-79-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bicyclo[6.1.0]nonyne-O-succinimidyl ester; BCN-OSu; BCN-NHS ester; BCN-Active Ester; (1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl N-succinimidyl carbonate; Dibenzocyclooctyne-succinimidyl ester derivative; DBCO-sulfo-NHS ester analog; Strain-promoted alkyne-NHS ester
EINECS	Contact for details

Quality Control

Our Bcn-Osu is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its moisture-sensitive and potentially light-sensitive nature. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.