Description

(4-Methyl-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Benzo[D]Imidazol-5-Yl)Methanamine is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, including potential candidates for oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of complex drug molecules and investigational new drugs (INDs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Bioconjugation & Probe Development: The amine functional group enables its use in creating labeled compounds for biochemical and diagnostic research.
• Academic Research: Employed in university and institutional labs for heterocyclic chemistry studies and novel synthetic methodology development.

Basic Information

Product Name	(4-Methyl-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Benzo[D]Imidazol-5-Yl)Methanamine
CAS No.	1425933-32-9
Molecular Formula	C14H19N3O
Molecular Weight	245.32 g/mol
Synonyms	1-(Tetrahydro-2H-pyran-2-yl)-4-methyl-1H-benzimidazole-5-methanamine; 5-(Aminomethyl)-1-(tetrahydro-2H-pyran-2-yl)-4-methyl-1H-benzimidazole; (4-Methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-5-yl)methanamine; THP-protected benzimidazole amine; 1H-Benzimidazole-5-methanamine, 4-methyl-1-(tetrahydro-2H-pyran-2-yl)-; 1425933-32-9; 4-Methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-benzimidazole-5-methanamine
EINECS	Contact for details

Quality Control

Our (4-Methyl-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Benzo[D]Imidazol-5-Yl)Methanamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, and NMR. We adhere to ICH guidelines for stability and impurity characterization to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.