Description

1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-1,2,3-Triazole is a high-value, functionalized heterocyclic building block that integrates a triazole core with a protected boronic ester moiety. This compound matters as a critical intermediate in modern synthetic chemistry, enabling efficient cross-coupling reactions for the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in drug discovery, ligand synthesis, and polymer modification.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and herbicides.
• Materials Science: Precursor for functional polymers, metal-organic frameworks (MOFs), and advanced organic electronic materials.
• Chemical Biology & Bioconjugation: Enables the site-specific modification of biomolecules and the development of chemical probes.
• Ligand & Catalyst Development: Serves as a precursor for creating novel N-heterocyclic carbene (NHC) ligands and organometallic catalysts.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-1,2,3-Triazole
CAS No.	1423123-94-7
Molecular Formula	C10H18BN3O2
Molecular Weight	223.09 g/mol
Synonyms	1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-1,2,3-triazole; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-1,2,3-triazole; 1-Methyl-1H-1,2,3-triazole-4-boronic acid pinacol ester; 1-Methyl-4-(pinacolatoboryl)-1H-1,2,3-triazole; 1-Methyl-1,2,3-triazol-4-ylboronic acid pinacol ester; 1-Methyl-4-(pinacol boronate)-1H-1,2,3-triazole; 1-Methyl-4-(pinacolato)boryl-1H-1,2,3-triazole; 1-Methyl-4-(pinacolboron)-1H-1,2,3-triazole
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-1,2,3-Triazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with ISO standards and the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.