Description

1-(Bromomethyl)-1-(Methanesulfonylmethyl)Cyclobutane is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclobutane scaffold functionalized with bromomethyl and methanesulfonylmethyl groups. This compound is valued for its role as a versatile building block in modern organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring a functionalized cyclobutane core.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its reactive bromomethyl group allows for further derivatization.
• Material Science: Serves as a precursor for specialty polymers and advanced materials with tailored properties.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions due to its reactive halogen and sulfone functionalities.
• Ligand and Catalyst Development: Useful for constructing novel chelating ligands or organocatalysts in asymmetric synthesis.
• Chemical Biology: Acts as a probe or linker molecule in bioconjugation and proteomics research.

Basic Information

Product Name	1-(Bromomethyl)-1-(Methanesulfonylmethyl)Cyclobutane
CAS No.	1423031-60-0
Molecular Formula	C8H15BrO2S
Molecular Weight	255.17 g/mol
Synonyms	1-(Bromomethyl)-1-[(methylsulfonyl)methyl]cyclobutane; Cyclobutane, 1-(bromomethyl)-1-[(methylsulfonyl)methyl]-; 1-Bromomethyl-1-methanesulfonylmethyl-cyclobutane; (Bromomethyl)(methanesulfonylmethyl)cyclobutane; MSM-Br Cyclobutane; α-Bromo-α-(methylsulfonylmethyl)cyclobutane; 1-(Bromomethyl)-1-(methylsulfonylmethyl)cyclobutane
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-1-(Methanesulfonylmethyl)Cyclobutane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for your research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.