Description

(3-Iodo-1H-Indazol-7-Yl)-Methanol is a high-purity, functionalized indazole derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and valuable building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its reactive iodine and hydroxymethyl functional groups.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce the indazole moiety into more complex molecules.
• Chemical Biology Probes: Can be utilized in the synthesis of chemical probes for studying biological pathways and target engagement.
• Agrochemical Development: Acts as a precursor in the synthesis of novel active ingredients for crop protection.
• Material Science Research: Potential building block for organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	(3-Iodo-1H-Indazol-7-Yl)-Methanol
CAS No.	1422772-72-2
Molecular Formula	C8H7IN2O
Molecular Weight	274.06 g/mol
Synonyms	7-(Hydroxymethyl)-3-iodo-1H-indazole; 3-Iodo-1H-indazole-7-methanol; 1H-Indazole-7-methanol, 3-iodo-; (3-Iodo-1H-indazol-7-yl)methanol; 3-Iodo-7-hydroxymethyl-1H-indazole; 7-Hydroxymethyl-3-iodoindazole; 1422772-72-2; (3-Iodoindazol-7-yl)methanol
EINECS	Contact for details

Quality Control

Our (3-Iodo-1H-Indazol-7-Yl)-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.