Description

5-Benzofuranacetamide, 2-[(S)-(3,5-Dimethyl-4-Isoxazolyl)Hydroxymethyl]-n-[(S)-(2,4-Dimethylphenyl)Phenylmethyl]- is a sophisticated chiral organic compound featuring a benzofuran core linked to an isoxazole and a substituted phenylmethyl group. This complex molecular architecture makes it a valuable high-purity intermediate for advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug discovery programs.
• Chemical Synthesis Reagent: Used in advanced organic synthesis for constructing complex heterocyclic frameworks due to its benzofuran and isoxazole functionalities.
• Asymmetric Catalysis Studies: Serves as a substrate or ligand precursor in the development and testing of new asymmetric catalytic reactions, leveraging its defined stereocenters.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical manufacturing.
• Biochemical Research: Investigated for its potential biological activity and interactions with specific enzymes or receptors in early-stage pharmacological studies.
• Process Chemistry Development: Used to optimize scalable synthetic routes for the production of target molecules in pilot plants and commercial manufacturing settings.

Basic Information

Item	Details
Product Name	5-Benzofuranacetamide, 2-[(S)-(3,5-Dimethyl-4-Isoxazolyl)Hydroxymethyl]-n-[(S)-(2,4-Dimethylphenyl)Phenylmethyl]-
CAS No.	1422053-04-0
Molecular Formula	C31H32N2O4
Molecular Weight	496.60 g/mol
Synonyms	2-[(S)-(3,5-Dimethyl-4-isoxazolyl)hydroxymethyl]-N-[(S)-(2,4-dimethylphenyl)phenylmethyl]-5-benzofuranacetamide; (S)-N-((S)-(2,4-Dimethylphenyl)(phenyl)methyl)-2-((3,5-dimethylisoxazol-4-yl)(hydroxy)methyl)-1-benzofuran-5-carboxamide; UNII-1K1W8F4J9G; 1K1W8F4J9G; BDBM50382875; AKOS025310957; ZINC00025310957; CHEMBL3186662
EINECS	Contact for details

Quality Control

Our 5-Benzofuranacetamide intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.