Description

1-Bromo-4-Fluoroisoquinoline is a high-purity, halogenated isoquinoline derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an exceptionally valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, material science, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced organic electronic materials, such as OLEDs and organic semiconductors.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis, including cross-coupling reactions like Suzuki-Miyaura and Buchwald-Hartwig amination.
• Chemical Biology Probe Development: Utilized as a scaffold for creating fluorescent tags or photoaffinity labels to study biological processes and protein interactions.
• Academic & Contract Research: Essential for exploratory synthetic chemistry in university laboratories and contract research organizations (CROs) focused on novel heterocyclic chemistry.

Basic Information

Item	Details
Product Name	1-Bromo-4-Fluoroisoquinoline
CAS No.	1421517-86-3
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	4-Fluoro-1-bromoisoquinoline; 1-Bromo-4-fluoroisoquinoline; Isoquinoline, 1-bromo-4-fluoro-; 1421517-86-3; 4-Fluoro-1-bromo-isoquinoline; 1-Bromo-4-fluoro-isoquinoline
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-4-Fluoroisoquinoline is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical purity and consistency to meet the stringent requirements of research and pre-clinical development. A detailed Certificate of Analysis (COA) providing results for identity, purity, and impurity profiles is supplied with each shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.