Description

4-Hydroxy-1-Methyl-7-Phenoxy-3-Isoquinolinecarboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in developing new drug candidates and proprietary chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• API Synthesis: Serves as a core scaffold for constructing complex molecules with potential therapeutic activity in oncology, neurology, or anti-infective research.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new chemical reactions and developing novel synthetic methodologies involving isoquinoline derivatives.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals where high structural precision and purity are paramount.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4-Hydroxy-1-Methyl-7-Phenoxy-3-Isoquinolinecarboxylic Acid Methyl Ester
CAS No.	1421312-34-6
Molecular Formula	C18H15NO4
Molecular Weight	309.32 g/mol
Synonyms	Methyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate; 1-Methyl-7-phenoxy-4-hydroxyisoquinoline-3-carboxylic acid methyl ester; 4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester; 7-Phenoxy-1-methyl-4-hydroxyisoquinoline-3-carboxylic acid methyl ester; 3-Isoquinolinecarboxylic acid, 4-hydroxy-1-methyl-7-phenoxy-, methyl ester; CAS 1421312-34-6
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-1-Methyl-7-Phenoxy-3-Isoquinolinecarboxylic Acid Methyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.