Description

8-Bromo-7-Fluoroquinoline is a high-value, multi-functional halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its precise molecular architecture, featuring both bromine and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinolone-based antibiotics, anticancer agents, and other therapeutic compounds.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other electronic materials due to its electron-deficient aromatic system.
• Chemical Synthesis: The bromine atom provides an excellent handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Heck), while the fluorine atom can modulate lipophilicity and metabolic stability.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A versatile reagent for methodological studies and exploratory chemistry in both academic and corporate research laboratories.

Basic Information

Product Name	8-Bromo-7-Fluoroquinoline
CAS No.	1420790-22-2
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	7-Fluoro-8-bromoquinoline; 8-Bromo-7-fluoroquinoline; Quinoline, 8-bromo-7-fluoro-; 8-Bromo-7-fluoro-quinoline; 1420790-22-2 (CAS); 8-Br-7-F-quinoline
EINECS	Contact for details

Quality Control

Every batch of 8-Bromo-7-Fluoroquinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.