Description

5-Amino-1-Boc-Hexahydrocyclopenta[B]Pyrrole is a high-purity, protected amine derivative that serves as a critical chiral building block in advanced organic synthesis. This compound matters because it provides a versatile and stereochemically defined scaffold for constructing complex molecules, enabling the development of novel pharmaceuticals and agrochemicals. Pharmaceutical R&D and fine chemical manufacturers need this Boc-protected intermediate for the efficient synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral drugs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in medicinal chemistry programs.
• API Development: Used in the research and production of Active Pharmaceutical Ingredients (APIs) targeting neurological and infectious diseases.
• Peptidomimetics & PROTACs: Serves as a constrained, bicyclic proline analog in the design of peptidomimetics and Proteolysis Targeting Chimeras (PROTACs).
• Agrochemical Synthesis: Employed as a building block for creating novel, high-value crop protection agents with specific biological activity.
• Asymmetric Catalysis Ligand Precursor: A potential precursor for chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Academic & Industrial R&D: Utilized in research laboratories for method development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	5-Amino-1-Boc-Hexahydrocyclopenta[B]Pyrrole
CAS No.	1419101-27-1
Molecular Formula	C₁₂H₂₂N₂O₂
Molecular Weight	226.32 g/mol
Synonyms	1-Boc-5-aminohexahydrocyclopenta[b]pyrrole; tert-Butyl 5-aminohexahydrocyclopenta[b]pyrrole-1-carboxylate; 5-Amino-1-(tert-butoxycarbonyl)hexahydrocyclopenta[b]pyrrole; 1-N-Boc-5-aminohexahydrocyclopenta[b]pyrrole; 5-Amino-1-Boc-octahydrocyclopenta[b]pyrrole; (1R,3aS,6aR)-5-Amino-1-Boc-hexahydrocyclopenta[b]pyrrole (stereoisomer); (1S,3aR,6aS)-5-Amino-1-Boc-hexahydrocyclopenta[b]pyrrole (stereoisomer)
EINECS	Contact for details

Quality Control

Our 5-Amino-1-Boc-Hexahydrocyclopenta[B]Pyrrole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for specific enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.