Description

2-(3-Hydroxy-Piperidin-1-Yl)-1-Thiophen-2-Yl-Ethanone Hydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical manufacturers developing new therapeutic agents, especially within the fields of central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Synthesis: Serves as a versatile reagent for constructing complex heterocyclic compounds containing piperidine and thiophene moieties.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical assays and target validation studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Reference Standard: Suitable for use as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-(3-Hydroxy-Piperidin-1-Yl)-1-Thiophen-2-Yl-Ethanone Hydrochloride
CAS No.	1417793-20-4
Molecular Formula	C11H16ClNO2S
Molecular Weight	261.77 g/mol
Synonyms	1-(2-Thienyl)-2-(3-hydroxypiperidino)ethanone hydrochloride; 2-(3-Hydroxy-1-piperidinyl)-1-(2-thienyl)ethanone hydrochloride; 1-(Thiophen-2-yl)-2-(3-hydroxypiperidin-1-yl)ethanone hydrochloride; Ethanone, 1-(2-thienyl)-2-(3-hydroxy-1-piperidinyl)-, hydrochloride; 2-(3-Hydroxypiperidin-1-yl)-1-(thiophen-2-yl)ethanone HCl
EINECS	Contact for details

Quality Control

Our 2-(3-Hydroxy-Piperidin-1-Yl)-1-Thiophen-2-Yl-Ethanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, and can support development under ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.